N,N'-Dimethylethylenediamine → 4-Bromotriphenylamine

HRID 31958

反応式

HRID 31958 の反応式
CNCCNC.[C:7]1([NH:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1.[Br:20][C:21]1[CH:26]=[CH:25][C:24](I)=[CH:23][CH:22]=1>[Cu].C1(C)C(C)=CC=CC=1>[CH:17]1[CH:16]=[CH:15][C:14]([N:13]([C:24]2[CH:25]=[CH:26][C:21]([Br:20])=[CH:22][CH:23]=2)[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=2)=[CH:19][CH:18]=1

参加物

6

反応物 3

HCID 8070N,N'-DimethylethylenediamineHCID 11487DiphenylamineHCID 115221-Bromo-4-iodobenzene

生成物 1

HCID 6428384-Bromotriphenylamine収率 70.2%

試薬・触媒・溶媒 2

HCID 23978Copper触媒HCID 7237O-Xylene溶媒

実験手順

N,N′-dimethylethylenediamine 1.76 g was added to diphenylamine 16.9 g, 4-bromoiodobenzene 28.2 g sodium t-butoxide 14.4 g, copper powder 3.81 g and a xylene 100 ml solution, and the mixture was heated and refluxed for 24 hours under argon atmosphere. After cooled down to room temperature, the mixture was filtered to remove an insoluble matter, and the filtrate was concentrated. The residue was refined by silica gel chromatography to obtain 22.7 g of white crystal of 4-bromotriphenylamine.

後処理

  1. temperaturerefluxed for 24 hours under argon atmosphere
  2. filtrationthe mixture was filtered
  3. customto remove an insoluble matter
  4. concentrationthe filtrate was concentrated

出典と根拠

ORDレコード
ord-aff8d328fb5246128c3497ee689c6469
出典データセット
uspto-grants-2008_09
特許番号
US07425654B2

関連ノート

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