Thionyl Chloride → 6-{3-[1-(3-Trifluoromethylphenyl)-cyclopropyl]-2-oxo-propionylamino}-4-methyl-2,3-benzoxazin-1-one

反応式

[C:37]([N:38]([CH3:39])[CH3:40])(=[O:41])[CH3:42].[F:5][C:6]([c:7]1[cH:8][c:9]([C:13]2([CH2:16][C:17]([C:18](=[O:19])[OH:20])=[O:21])[CH2:14][CH2:15]2)[cH:10][cH:11][cH:12]1)([F:22])[F:23].[NH2:24][c:25]1[cH:26][cH:27][c:28]2[c:29]([c:30]([CH3:35])[n:31][o:32][c:33]2=[O:34])[cH:36]1.[S:1]([Cl:2])([Cl:3])=[O:4]>>[F:5][C:6]([c:7]1[cH:8][c:9]([C:13]2([CH2:16][C:17]([C:18](=[O:20])[NH:24][c:25]3[cH:26][cH:27][c:28]4[c:29]([c:30]([CH3:35])[n:31][o:32][c:33]4=[O:34])[cH:36]3)=[O:21])[CH2:14][CH2:15]2)[cH:10][cH:11][cH:12]1)([F:22])[F:23]