Water → 3-Amino-4-[4-(3-Pyridyl)Anilino]-3-Cyclobutene-1,2-Dione
反応式
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:9]=[N:10][CH:11]=[CH:12][CH:13]=2)=[CH:4][CH:3]=1.[NH2:14][C:15]1[C:16](=[O:23])[C:17](=[O:22])[C:18]=1OCC.O>N1C=CC=CC=1>[NH2:14][C:15]1[C:16](=[O:23])[C:17](=[O:22])[C:18]=1[NH:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[CH:9]=[N:10][CH:11]=[CH:12][CH:13]=2)=[CH:6][CH:7]=1参加物
5
実験手順
A solution of 3-(4-aminophenyl)pyridine (0.51 g) and 3-amino-4-ethoxy-3-cyclobutene 1,2-dione (0.42 g) in pyridine (2 ml) is stirred at 80° for 20 hours. The cool mixture is treated with water (15 ml), and the solid filtered off and washed with water and hot methanol. Recrystallation from dimethylformamide gives 0.33 g of the title compound, mp 3224° C. dec.
後処理
- filtrationthe solid filtered off
- washwashed with water and hot methanol
出典と根拠
- ORDレコード
- ord-aa05ba3bd85e44dba5f6ce3a32446e72
- 出典データセット
- uspto-grants-2001_04
- 特許番号
- US06211220B1
反応ノート
読み込み中…