1,3-Dichloroacetone → HCID 22009841、化合物
反応式
[Cl:1][C:2]1[S:6][C:5]([C:7]([NH2:9])=[O:8])=[CH:4][CH:3]=1.[Cl:10][CH2:11][C:12]([CH2:14]Cl)=O>>[Cl:10][CH2:11][C:12]1[N:9]=[C:7]([C:5]2[S:6][C:2]([Cl:1])=[CH:3][CH:4]=2)[O:8][CH:14]=1参加物
3
実験手順
In substantially the same manner as in Reference Example 47, 5-chloro-2-thiophenecarboxamide was allowed to react with 1,3-dichloroacetone to give 4-chloromethyl-2-(5-chloro-2-thienyl)oxazole. The yield was 51%. Recrystallization from ethyl acetate-hexane gave colorless needles, mp 90-91° C.
出典と根拠
- ORDレコード
- ord-ca571d66ea8e46328eeb687e4f348840
- 出典データセット
- uspto-grants-2001_04
- 特許番号
- US06211215B1
反応ノート
読み込み中…