Magnesium Bromide → 2-(2,2,2-Trifluoroethoxy)ethan-1-ol
反応式
[F:1][C:2]([F:15])([F:14])[CH2:3][O:4][CH2:5][CH2:6][O:7]C1CCCCO1.[Br-].[Mg+2].[Br-]>C(OCC)C>[F:1][C:2]([F:15])([F:14])[CH2:3][O:4][CH2:5][CH2:6][OH:7]参加物
4
実験手順
Combine 2-tetrahydropyran-2-yloxyethyl 2,2,2-trifluorethyl ether (2 mmol) and magnesium bromide (6 mmol) in diethyl ether (10 mL). After 24 hours, extract with water and then brine. Dry the organic layer over Na2SO4, filter, and concentrate in vacuo to give 2-hydroxyethyl 2,2,2-trifluorethyl ether.
後処理
- extractionextract with water
- dry with materialDry the organic layer over Na2SO4
- filtrationfilter
- concentrationconcentrate in vacuo
出典と根拠
- ORDレコード
- ord-548a260dea404a5c8c1788cbebc98700
- 出典データセット
- uspto-grants-2001_04
- 特許番号
- US06211199B1
反応ノート
読み込み中…