Water → HCID 10499321、化合物

HRID 324020ノート

反応式

HRID 324020 の反応式
Cl[C:2]1[CH:7]=[C:6]([C:8]2[C:17]3[C:12](=[CH:13][C:14]([O:21][CH3:22])=[C:15]([O:18][CH2:19][CH3:20])[CH:16]=3)[CH:11]=[C:10]([CH2:23][OH:24])[C:9]=2[CH2:25][OH:26])[CH:5]=[CH:4][N:3]=1.O.O.[NH2:29][NH2:30]>>[NH:29]([C:2]1[CH:7]=[C:6]([C:8]2[C:17]3[C:12](=[CH:13][C:14]([O:21][CH3:22])=[C:15]([O:18][CH2:19][CH3:20])[CH:16]=3)[CH:11]=[C:10]([CH2:23][OH:24])[C:9]=2[CH2:25][OH:26])[CH:5]=[CH:4][N:3]=1)[NH2:30]

参加物

4

反応物 3

HCID 962WaterHCID 24654Hydrazine hydrate (1:1)HCID 10738129HCID 10738129、化合物

生成物 1

HCID 10499321HCID 10499321、化合物

実験手順

A suspension of 1-(2-chloro-4-pyridyl)-2,3-bis(hydroxymethyl)-6-methoxy-7-ethoxynaphthalene (16.0 g) in hydrazine hydrate (50 ml) is refluxed for four hours. The mixture is cooled to room temperature, and then thereto is added water. The precipitated crystals are collected by filtration, washed with water, and dried to give 1-(2-hydrazino-4-pyridyl)-2,3-bis(hydroxymethyl)-6-methoxy-7-ethoxynaphthalene (14.5 g).

後処理

  1. temperatureis refluxed for four hours
  2. filtrationThe precipitated crystals are collected by filtration
  3. washwashed with water
  4. customdried

出典と根拠

ORDレコード
ord-07315e3ab0da4347a10d5e6fe0e4f108
出典データセット
uspto-grants-2001_04
特許番号
US06214996B1

反応ノート

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