Hydrochloric Acid → 6-Carbamoyl-2,3-dihydro-1,4-phthalazinedione
反応式
[C:1]([C:4]1[CH:5]=[C:6]2[C:11](=[O:12])[NH:10][C:8](=[O:9])[C:7]2=[CH:13][CH:14]=1)(=[O:3])[NH2:2].O.[NH2:16]N.Cl.O>CN1CCCC1=O>[C:1]([C:4]1[CH:5]=[C:6]2[C:7](=[CH:13][CH:14]=1)[C:8](=[O:9])[NH:16][NH:10][C:11]2=[O:12])(=[O:3])[NH2:2]参加物
6
実験手順
4-Carbamoylphthalimide (2.00 g, 0.011 mol) was suspended in 12 ml of N-methyl-2-pyrrolidinone, followed by the dropwise addition of 0.8 ml of hydrazine hydrate. The obtained mixture was stirred at room temperature for 30 minutes, followed by the addition of 5.5 ml of 3N hydrochloric acid and 50 ml of water. The crystals thus precipitated were recovered by filtration, washed with water and dried with hot air. The title compound (2.0 g) was obtained as a light brown crystal (yield: 94%).
後処理
- customThe crystals thus precipitated
- filtrationwere recovered by filtration
- washwashed with water
- customdried with hot air
出典と根拠
- ORDレコード
- ord-518c10f112d94cb6ad72531aa90f392c
- 出典データセット
- uspto-grants-2001_04
- 特許番号
- US06218392B1
反応ノート
読み込み中…