化工社化工社 化学情報印刷レポート · 研究参考用
1-Methyluracil → HCID 178432331、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Methyluracil | HCID 12009 | — |
| 反応物 | 2-Methyl-1-(4-methoxyphenylmethyl)-4H-benzo[5,6]cyclohepta[1,2-d]imidazol-4-ol | HCID 22003671 | — |
| 溶媒 | Trifluoroacetic acid | HCID 6422 | — |
| 生成物 | HCID 178432331 | HCID 178432331 | — |
反応手順
A stirred solution of the product from step (iii) (0.819 g) in trifluoroacetic acid (20 ml) was heated at reflux for 1 h. 1-Methyluracil (0.311 g) was added and the reflux continued for 5 days. The solvent was evaporated under reduced pressure. The residue was purified by chromatography eluting with 10% methanol in dichloromethane to give the subtitle product as pale green glass.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06218376B1 |
| 出典データセット | uspto-grants-2001_04 |
| ORD ID | ord-a866e5d4415144668ea8de1cb16098af |
| 出典メモ | uspto-grants-2001_04 |