Triethylamine → HCID 22003670、化合物
反応式
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[C:15](=[O:16])[C:10]3[N:11]=[C:12]([CH3:14])[S:13][C:9]=3[CH2:8][CH2:7][C:6]=2[CH:17]=1.BrN1C(=O)CCC1=O.C(N(CC)CC)C>ClCCCl>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[C:15](=[O:16])[C:10]3[N:11]=[C:12]([CH3:14])[S:13][C:9]=3[CH:8]=[CH:7][C:6]=2[CH:17]=1参加物
5
実験手順
A solution of the product from step (i) (6.05 g) in 1,2-dichloroethane (85 ml) with N-bromosuccinimide (4.1 g) was irradiated with a 500 Watt halogen lamp for 1 h. After cooling to room temperature, triethylamine (7 ml) was added with further stirring for 0.5 hours. The solvents were evaporated under reduced pressure and the residue triturated with acetone, filtered and then further washed with water and then dried under vacuum to leave the subtitle compound as a cream solid.
後処理
- customThe solvents were evaporated under reduced pressure
- customthe residue triturated with acetone
- filtrationfiltered
- washfurther washed with water
- customdried under vacuum
出典と根拠
- ORDレコード
- ord-d10f2582a59744f2b48bac43a44d3950
- 出典データセット
- uspto-grants-2001_04
- 特許番号
- US06218376B1
反応ノート
読み込み中…