化工社化工社 化学情報印刷レポート · 研究参考用
Hydrazine hydrate (1:1) → HCID 178507266、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 反応物 | 3-Cyclopropyl-3-oxopropanenitrile | HCID 9812763 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | HCID 178507266 | HCID 178507266 | 80% |
反応手順
5 g (0.046 mol) of 3cyclopropyl-3-oxo-propanenitrile were dissolved in 200 ml of ethanol and 2.26 ml (0.046 mol) of hydrazine hydrate were added. The solution was maintained at reflux for 5 hours and then the solvent evaporated under vacuum. The residue was re-dissolved with methylene chloride and washed several times with brine. The organic layer was dried over anhydrous sodium sulfate and the solvent evaporated to give 4.53 g (80% yield) of the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06218418B1 |
| 出典データセット | uspto-grants-2001_04 |
| ORD ID | ord-154fbe4b82e84bcda85fd24c5d81902f |
| 出典メモ | uspto-grants-2001_04 |