Water → 2-Propyl-6-heptenoic acid
反応式
[CH2:1]([CH:4]([CH2:9][CH2:10][CH2:11][CH:12]=[CH2:13])[C:5]([O:7]C)=[O:6])[CH2:2][CH3:3].[OH-].[Na+].O>C(O)C>[CH2:1]([CH:4]([CH2:9][CH2:10][CH2:11][CH:12]=[CH2:13])[C:5]([OH:7])=[O:6])[CH2:2][CH3:3]参加物
5
実験手順
A mixture of methyl 2-propyl-6-heptenoate (1.8 g), sodium hydroxide (0.65 g), water (2 ml) and ethanol (100 ml) was heated under reflux for 2 hours. The solvent was removed under reduced pressure and the resulting residue was shaken with water and hexane. The aqueous layer was acidified with concentrated hydrochloric acid and extracted with ethyl acetate. The organic layer was dried and concentrated to give oil of 2-propyl-6-heptenoic acid (1.25 g).
後処理
- temperaturewas heated
- temperatureunder reflux for 2 hours
- customThe solvent was removed under reduced pressure
- extractionextracted with ethyl acetate
- customThe organic layer was dried
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-a2d9b0c1f6984e6f81515ebe112d4275
- 出典データセット
- uspto-grants-1984_04
- 特許番号
- US04443365
反応ノート
読み込み中…