Benzyl Alcohol → Benzyl 3-oxo-5-phenylpentanoate

HRID 326196

反応式

HRID 326196 の反応式
[O:1]=[C:2]([CH2:9][CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[CH2:3][C:4]([O:6][CH2:7][CH3:8])=[O:5].C(O)[C:18]1[CH:23]=[CH:22]C=[CH:20][CH:19]=1>C(O)C>[O:1]=[C:2]([CH2:9][CH2:10][C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=1)[CH2:3][C:4]([O:6][CH2:7][C:8]1[CH:22]=[CH:23][CH:18]=[CH:19][CH:20]=1)=[O:5]

参加物

4

反応物 2

HCID 244Benzyl AlcoholHCID 61162Ethyl 3-oxo-5-phenylpentanoate

生成物 1

HCID 13055807Benzyl 3-oxo-5-phenylpentanoate

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

Ethyl 3-oxo-5-phenylpentanoate (64.2 g, 0.29 mole) was heated between 190° and 210° C. under nitrogen with benzyl alcohol (28.9 ml, 0.28 mole) for 6 hours, the ethanol formed being distilled out of the reaction mixture. The resulting pale yellow oil was essentially pure product, slightly contaminated by starting materials, n.m.r. δ(CCl4) 7.23 (5H, s), 7.06 (5H, s), 5.03 (2H, s), 3.23 (2H, s) and 2.73 (4H, s).

後処理

  1. distillationbeing distilled out of the reaction mixture

出典と根拠

ORDレコード
ord-f813d5d350fc4144b00499e53ec2a0bc
出典データセット
uspto-grants-1984_04
特許番号
US04444981

関連ノート

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