Pyrrolidine → 2-Chloro-5-(pyrrolidine-1-sulfonyl)benzoic acid
反応式
[Cl:1][C:2]1[CH:10]=[CH:9][C:8]([S:11](=[O:15])(=[O:14])[NH:12][CH3:13])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].Cl[C:17]1[CH:25]=CC(S(O)=O)=C[C:18]=1C(O)=O.N1CCCC1>>[Cl:1][C:2]1[CH:10]=[CH:9][C:8]([S:11]([N:12]2[CH2:25][CH2:17][CH2:18][CH2:13]2)(=[O:15])=[O:14])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5]参加物
4
実験手順
The title compound was synthesised according to the procedure described for 2-Chloro-5-methylsulfamoyl-benzoic acid from 2-Chloro-5-sulfino-benzoic acid and pyrrolidine and obtained in 91% yield. MS (m/e): 288.0 (MH−, 100%).
後処理
- customobtained in 91% yield
出典と根拠
- ORDレコード
- ord-1e11387398a648819116aeffaedeb567
- 出典データセット
- uspto-grants-2008_09
- 特許番号
- US07427612B2
反応ノート
読み込み中…