Sodium Hydroxide → 3-(Pyrrolidine-1-carbonyl)thiomorpholine
反応式
[OH-].[Na+].Cl.[N:4]1([C:9]([CH:11]2[CH2:16][S:15][CH2:14][CH2:13][NH:12]2)=[O:10])[CH2:8][CH2:7][CH2:6][CH2:5]1>C(Cl)Cl>[N:4]1([C:9]([CH:11]2[CH2:16][S:15][CH2:14][CH2:13][NH:12]2)=[O:10])[CH2:5][CH2:6][CH2:7][CH2:8]1参加物
4
実験手順
A 1N aqueous sodium hydroxide solution (12.5 ml) was added to a mixture of 2.47 g of 3-(pyrrolidine-1-carbonyl)thiomorpholine monohydrochloride and 20 ml of methylene chloride. The organic layer was extracted and dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure to yield 1.75 g (83%) of 3-(pyrrolidine-1-carbonyl)thiomorpholine
後処理
- extractionThe organic layer was extracted
- dry with materialdried over anhydrous magnesium sulfate
- customThe solvent was evaporated under reduced pressure
出典と根拠
- ORDレコード
- ord-c51eba5ded984a67bf21a23a08f822ac
- 出典データセット
- uspto-grants-1993_12
- 特許番号
- US05270327
反応ノート
読み込み中…