Diphosgene → 5-Isocyanato-1,2,3-trimethoxybenzene

HRID 327492

反応式

HRID 327492 の反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:7]=[C:8]([O:12][CH3:13])[C:9]=1[O:10][CH3:11])[NH2:6].Cl[C:15](OC(Cl)(Cl)Cl)=[O:16]>C1(C)C=CC=CC=1>[CH3:13][O:12][C:8]1[CH:7]=[C:5]([N:6]=[C:15]=[O:16])[CH:4]=[C:3]([O:2][CH3:1])[C:9]=1[O:10][CH3:11]

参加物

4

反応物 2

HCID 10426DiphosgeneHCID 322853,4,5-Trimethoxyaniline

生成物 1

HCID 5177665-Isocyanato-1,2,3-trimethoxybenzene

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒2 回

実験手順

600 ml of a solution of 18.3 g of 3,4,5-trimethoxyaniline in toluene was added to 140 ml of a solution of 48 ml of trichloromethyl chloroformate in toluene and the mixture was refluxed for 3 h. After cooling, the solvent was distilled off and the residue was distilled under reduced pressure (115° C./l mmHg) to obtain 15.53 g of 3,4,5-trimethoxyphenyl isocyanate.

後処理

  1. temperaturethe mixture was refluxed for 3 h
  2. temperatureAfter cooling
  3. distillationthe solvent was distilled off
  4. distillationthe residue was distilled under reduced pressure (115° C./l mmHg)

出典と根拠

ORDレコード
ord-19d3c568dd6c4df8b444e7c37ed58e21
出典データセット
uspto-grants-1993_12
特許番号
US05273985

関連ノート

読み込み中…