Potassium ethylxanthate → HCID 178505573、化合物

HRID 327779ノート

反応式

HRID 327779 の反応式
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([F:8])[C:3]=1[NH2:9].CCO[C:13]([S-])=[S:14].[K+]>C(O)C.O>[F:8][C:4]1[C:3]2[N:9]=[C:13]([SH:14])[NH:1][C:2]=2[CH:7]=[CH:6][CH:5]=1

参加物

5

反応物 2

HCID 2735045Potassium ethylxanthateHCID 27828353-Fluorobenzene-1,2-diamine

生成物 1

HCID 178505573HCID 178505573、化合物

試薬・触媒・溶媒 2

HCID 702Ethanol溶媒HCID 962Water溶媒

実験手順

1,2-diamino-3-fluorobenzene (1.6 g, 12.7 mmol) and potassium ethyl xanthogenate (2.64 g, 16.5 mmol) were dissolved in ethanol (25 ml) and water (6 ml). The mixture was refluxed for 14 hours and then concentrated on a rotavapor. Water (20 ml) was added and the solution was acidified with 2M hydrochloric acid. The precipitate was filtered off and dried. In this way the title compound was obtained (1.23 g, 58%). NMR is given below.

後処理

  1. temperatureThe mixture was refluxed for 14 hours
  2. concentrationconcentrated on a rotavapor
  3. additionWater (20 ml) was added
  4. filtrationThe precipitate was filtered off
  5. customdried

出典と根拠

ORDレコード
ord-40645df9b5a5419f897a6ce588ca7b3d
出典データセット
uspto-grants-1993_12
特許番号
US05274099

反応ノート

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