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Furo(3,4-b)pyrazine-5,7-dione → (1-Ethyl-2-methylindol-3-yl)-(2-carboxypyrazin-3-yl)ketone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Furo(3,4-b)pyrazine-5,7-dione | HCID 78482 | — |
| 反応物 | 1-Ethyl-2-methyl-1H-benzo[G]indole | HCID 15114396 | — |
| 生成物 | (1-Ethyl-2-methylindol-3-yl)-(2-carboxypyrazin-3-yl)ketone | HCID 20534320 | 16.2% |
反応手順
The appropriate keto-acid is prepared as follows. A mixture of about 6 grams of 2,3-pyrazinedicarboxylic anhydride and about 10.5 grams of 1-ethyl-2-methyl-1H-benz[g]indole is heated on a steam bath for about 24 hours. The mixture is extracted with toluene. About 2 grams of (1-ethyl-2-methylindol-3-yl)-(2-carboxypyrazin-3-yl)ketone is obtained having a melting point of 212°-213° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04016174 |
| 出典データセット | uspto-grants-1977_04 |
| ORD ID | ord-0f984a2661954e6489dd9836d234c9c2 |
| 出典メモ | uspto-grants-1977_04 |