Hydrochloric Acid → 4'-Hexyl[1,1'-biphenyl]-4-carboxylic acid

HRID 328305ノート

反応式

HRID 328305 の反応式
[CH2:1]([C:7]1[CH:12]=[CH:11][C:10]([C:13]2[CH:18]=[CH:17]C(C#N)=[CH:15][CH:14]=2)=[CH:9][CH:8]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].C(O)CO[CH2:24][CH2:25][OH:26].[OH-:28].[Na+].Cl>O>[CH2:1]([C:7]1[CH:12]=[CH:11][C:10]([C:13]2[CH:18]=[CH:17][C:24]([C:25]([OH:26])=[O:28])=[CH:15][CH:14]=2)=[CH:9][CH:8]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]

参加物

6

反応物 4

HCID 313Hydrochloric AcidHCID 8117Diethylene GlycolHCID 14798Sodium HydroxideHCID 38764(1,1'-Biphenyl)-4-carbonitrile, 4'-hexyl-

生成物 1

HCID 135545884'-Hexyl[1,1'-biphenyl]-4-carboxylic acid

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

5 Gram of 4-n-hexyl-4'-cyanobiphenyl, 40 ml of diethylene glycol, 4 ml of water and 2 g of sodium hydroxide were introduced into 200 ml three neck flask and heated with stirring for 25 hours, followed by acidifying with hydrochloric acid, separating by filtration and recrystallizing with glacial acetic acid to give 4.1 g of 4-n-hexyl-biphenyl-4'-carboxylic acid (II), which was a colorless crystal having a molecular formula of C19H22O2 (composition: C 80.8%, H 7.9%, O 11.3% as calculated values and C 80.4%, H 8.1%, O 11.5% as observed values) and a melting point of 170° -171° C and formed a smectic liquid crystal at temperatures exceeding the melting point.

後処理

  1. temperatureheated
  2. customseparating by filtration
  3. customrecrystallizing with glacial acetic acid

出典と根拠

ORDレコード
ord-baf99e0fdc284093a7109547019dea7d
出典データセット
uspto-grants-1977_04
特許番号
US04017416

反応ノート

読み込み中…