Hydrochloric Acid → N-[(4,6-dimethylpyrimidin-2-yl)aminocarbonyl]-2-ethoxyaminocarbonylbenzenesulfonamide

HRID 329757

反応式

HRID 329757 の反応式
C[Al](C)C.Cl.[CH2:6]([O:8][NH2:9])[CH3:7].[CH3:10][C:11]1[CH:16]=[C:15]([CH3:17])[N:14]=[C:13]([NH:18][C:19]([NH:21][S:22]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=2[C:31](OC)=[O:32])(=[O:24])=[O:23])=[O:20])[N:12]=1.Cl>C(Cl)Cl>[CH3:10][C:11]1[CH:16]=[C:15]([CH3:17])[N:14]=[C:13]([NH:18][C:19]([NH:21][S:22]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=2[C:31]([NH:9][O:8][CH2:6][CH3:7])=[O:32])(=[O:24])=[O:23])=[O:20])[N:12]=1

参加物

6

反応物 4

HCID 313Hydrochloric AcidHCID 52997Sulfometuron-methylHCID 76850O-ethylhydroxylamine hydrochlorideHCID 16682925Trimethylaluminum

生成物 1

HCID 19871558N-[(4,6-dimethylpyrimidin-2-yl)aminocarbonyl]-2-ethoxyaminocarbonylbenzenesulfonamide

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

To 2.9 g of trimethylaluminum in 100 ml of methylene chloride is added 2.0 g of ethoxyamine hydrochloride with stirring at ambient temperature. To this mixture is added 3.0 g of N-[(4,6-dimethylpyrimidin-2-yl)aminocarbonyl]-2-methoxycarbonylbenzenesulfonamide and the solution is refluxed for 18 hours. The reaction mixture is treated with aqueous hydrochloric acid and the resulting precipitated product is purified by chromatography.

後処理

  1. temperaturethe solution is refluxed for 18 hours
  2. customthe resulting precipitated product
  3. customis purified by chromatography

出典と根拠

ORDレコード
ord-a3ef8abf81d14e7cb104d6a293d44aef
出典データセット
uspto-grants-1990_01
特許番号
US04892946

関連ノート

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