Bromide ion → Perbenzoic acid

HRID 330093

反応式

HRID 330093 の反応式
[C:1]1([Se]Cl)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Br-].C1(S(Cl)=O)C=CC=CC=1.[OH:19][OH:20].C[CH2:22][O:23]CC>C(Cl)Cl>[C:22]([O:19][OH:20])(=[O:23])[C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

参加物

7

反応物 5

HCID 259Bromide ionHCID 784Hydrogen PeroxideHCID 3283Diethyl EtherHCID 21928Chloroselenobenzene2 回HCID 4190003Benzenesulfinyl chloride

生成物 1

HCID 523077Perbenzoic acid

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

反応条件

温度
0 °C

実験手順

The diene (2) of step (B) is treated with a halogenating agent such as phenylselenyl chloride or bromide or phenylsulfinyl chloride, preferably phenylselenyl chloride, in an approximately equimolar ratio in an inert solvent at about -80° C., for approximately 20 minutes; illustrative of such inert solvents are methylene chloride, ether and the like. After a standard workup the product residue is dissolved in an ethereal solvent, chilled to about 0° C. and oxidized with an agent such as 30% hydrogen peroxide or a peroxy acid such as peroxybenzoic acid to yield a halohydrin analog (3).

後処理

  1. dissolutionAfter a standard workup the product residue is dissolved in an ethereal solvent

出典と根拠

ORDレコード
ord-87cf1d353afc46b09fcef30e59489fe9
出典データセット
uspto-grants-1990_01
特許番号
US04894466

関連ノート

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