2-Propanethiol → HCID 19868700、化合物

HRID 330503

反応式

HRID 330503 の反応式
[OH:1][CH:2]1[NH:6][C:5](=O)[CH2:4][CH2:3]1.[CH3:8][CH:9]([SH:11])[CH3:10]>CCOCC>[CH:9]([S:11][CH:5]1[NH:6][C:2](=[O:1])[CH2:3][CH2:4]1)([CH3:10])[CH3:8]

参加物

4

反応物 2

HCID 63642-PropanethiolHCID 1941485-Hydroxy-2-pyrrolidone

生成物 1

HCID 19868700HCID 19868700、化合物

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

実験手順

A mixture of 9 g of 5-hydroxy-pyrrolidin-2-one in 40 cm3 of 2-propanethiol and 5 g of Amberlite resin IR 120 H is maintained for 80 hours at ambient temperature. After diluting with ether, filtering, and concentrating under reduced pressure, 8.5 g of the expected product is obtained. m.p. 77°-79° C., crystallized from isopropyl ether. m.p. 85°-87° C. after re-crystallization.

後処理

  1. filtrationfiltering
  2. concentrationconcentrating under reduced pressure

出典と根拠

ORDレコード
ord-305946d9a6094476881ff00344e5235f
出典データセット
uspto-grants-1990_01
特許番号
US04897414

関連ノート

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