3-methoxy-N-methyl-2-nitroaniline → 3-methoxy-N1-methylbenzene-1,2-diamine

HRID 330881ノート

反応式

HRID 330881 の反応式
[CH3:1][O:2][C:3]1[C:4]([N+:11]([O-])=O)=[C:5]([NH:9][CH3:10])[CH:6]=[CH:7][CH:8]=1>C(OCC)(=O)C.[Pd]>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([NH:9][CH3:10])[C:4]=1[NH2:11]

参加物

4

反応物 1

HCID 580715913-methoxy-N-methyl-2-nitroaniline

生成物 1

HCID 106069363-methoxy-N1-methylbenzene-1,2-diamine収率 95.4%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 8857Ethyl Acetate溶媒

実験手順

7.4 g (3-methoxy-2-nitrophenyl)-methylamine are suspended in 150 ml of ethyl acetate and hydrogenated with 1 g Pd/C 10% at a pressure of 50 psi and ambient temperature. After 4.5 hours the catalyst is suction filtered and the filtrate is evaporated to dryness. 5.9 g of the product are obtained as an oil.

後処理

  1. filtrationsuction filtered
  2. customthe filtrate is evaporated to dryness

出典と根拠

ORDレコード
ord-625595317ec14a42abdfa01e88c6f1b6
出典データセット
uspto-grants-2014_11
特許番号
US08877758B2

反応ノート

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