(S)-5-dibenzylamino-1-methylpiperidin-2-one → HCID 28064098、化合物
反応式
C([N:8](CC1C=CC=CC=1)[C@@H:9]1[CH2:14][N:13]([CH3:15])[C:12](=[O:16])[CH2:11][CH2:10]1)C1C=CC=CC=1>CO.[Pd]>[NH2:8][C@@H:9]1[CH2:14][N:13]([CH3:15])[C:12](=[O:16])[CH2:11][CH2:10]1参加物
4
実験手順
0.450 g (S)-5-dibenzylamino-1-methylpiperidin-2-one are suspended in 25 ml of methanol and hydrogenated with 0.150 g Pd/C 10% at a pressure of 3 bar and a temperature of 60° C. After 16 hours the catalyst is suction filtered and the filtrate is evaporated to dryness. 0.190 g of the product are obtained as an oil. 1H NMR (400 MHz, DMSO): 2.76 (3H, s).
後処理
- customa temperature of 60° C
- filtrationsuction filtered
- customthe filtrate is evaporated to dryness
出典と根拠
- ORDレコード
- ord-21f547f2884648eca1896d36e6c8d86b
- 出典データセット
- uspto-grants-2014_11
- 特許番号
- US08877758B2
反応ノート
読み込み中…