戻る
化工社化工社 化学情報印刷レポート · 研究参考用
HRID 33139作成日：2026年10月26日

6-Chloro-2-(piperazin-1-yl)-1,3-benzothiazole → [4-(6-Chloro-benzothiazol-2-yl)-piperazin-1-yl]-(2-isopropoxy-5-methanesulfonyl-phenyl)-methanone

https://huagongshe.com/reaction/33139

反応式

関与物質

役割名称HCID仕込み量
反応物6-Chloro-2-(piperazin-1-yl)-1,3-benzothiazoleHCID 2746595—
反応物2-Isopropoxy-5-methylsulfonylbenzoic acidHCID 21100237—
生成物[4-(6-Chloro-benzothiazol-2-yl)-piperazin-1-yl]-(2-isopropoxy-5-methanesulfonyl-phenyl)-methanoneHCID 11648903—

反応手順

Prepared in analogy to example 1.1 b) from 2-isopropoxy-5-methanesulfonyl-benzoic acid (Example 2.2) and 6-chloro-2-piperazin-1-yl-benzothiazole. The crude material was purified by chromatography (SiO2, CH2Cl2/MeOH=95/5) to yield the title compound as a yellowish solid. MS (m/e): 552.3 (M+CH3COOH+)

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07429585B2
出典データセットuspto-grants-2008_09
ORD IDord-5268c11bda30498b84116ce689da3065
出典メモuspto-grants-2008_09