Dimethylformamide → (3-Methyl-but-3-enyloxymethyl)-benzene

HRID 332071ノート

反応式

HRID 332071 の反応式
[CH:1]1[CH:6]=[CH:5][C:4]([CH2:7]Br)=[CH:3][CH:2]=1.[H-].[Na+].CN([CH:14]=[O:15])C>>[CH3:5][C:4](=[CH2:3])[CH2:7][CH2:14][O:15][CH2:7][C:4]1[CH:5]=[CH:6][CH:1]=[CH:2][CH:3]=1

参加物

4

反応物 3

HCID 6228DimethylformamideHCID 7498Benzyl BromideHCID 24758Sodium hydride

生成物 1

HCID 11095166(3-Methyl-but-3-enyloxymethyl)-benzene

実験手順

BnBr was added to the mixture of alcohol and NaH in DMF cooled in an ice bath. The mixture was stirred at room temperature overnight and the solid was filtered. The solvent was removed and the residue was purified by column chromatography to give compound 1.

後処理

  1. temperaturecooled in an ice bath
  2. filtrationthe solid was filtered
  3. customThe solvent was removed
  4. customthe residue was purified by column chromatography

出典と根拠

ORDレコード
ord-8b3cf9473ad641549a850aaa49a84708
出典データセット
uspto-grants-2014_11
特許番号
US08877796B2

反応ノート

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