関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Tert-butyl 2-diazoacetate | HCID 5097903 | — |
| 反応物 | 3-[2-(2-Methoxyethoxy)ethoxy]prop-1-yne | HCID 18381683 | — |
| 生成物 | HCID 178496244 | HCID 178496244 | — |
反応手順
To a solution containing approx. 2.5 g 3-[2-(2-Methoxy-ethoxy)-ethoxy]-propyne, 2.8 g Diazo-acetic acid tert-butyl ester were added and the mixture was heated to 70° C. for 5 days. Then the solution was concentrated under reduced pressure and directly purified by chromatography on silica eluting with a n-heptane/ethyl acetate gradient. Yield: 1.7 g.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07429581B2 |
|---|
| 出典データセット | uspto-grants-2008_09 |
|---|
| ORD ID | ord-5dcdf0e1a84744839a7df22d5b6dc47e |
|---|
| 出典メモ | uspto-grants-2008_09 |
|---|
