Hydrochloric Acid → HCID 18934956、化合物
反応式
[C:1]([CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][C:8]([NH:10][CH2:11][C:12]([OH:14])=[O:13])=[O:9])#[N:2].[OH-].[Na+].Cl.[Cl-].[Na+]>C(O)C.[Ni]>[NH2:2][CH2:1][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][C:8]([NH:10][CH2:11][C:12]([OH:14])=[O:13])=[O:9]参加物
7
実験手順
8.2 g (41.4·10-3 mol) of N-(6-cyanohexanoyl)-glycine are dissolved in 100 ml of ethanol, and 60 ml of 1M sodium hydroxide solution and 800 mg of Raney nickel are added. The mixture is then stirred under a hydrogen atmosphere, at room temperature and under a pressure of 3.5·105Pa, for 8 hours. When the reaction has ended, 20 ml of 1M hydrochloric acid are added and the mixture is concentrated under reduced pressure to give 10.2 g of a white pasty solid, which contains the expected salt and sodium chloride and which can be used without further purification in the next step.
後処理
- concentrationthe mixture is concentrated under reduced pressure
- customto give 10.2 g of a white pasty solid, which
- customcan be used without further purification in the next step
出典と根拠
- ORDレコード
- ord-ae97e9d0be094c7d859d65239405a8ff
- 出典データセット
- uspto-grants-1998_03
- 特許番号
- US05733928
反応ノート
読み込み中…