Triphenylstannane → HCID 11152734、化合物

HRID 333641

反応式

HRID 333641 の反応式
C1(C)C(C)=CC=CC=1.C1([SnH](C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.[C:28]([C:31]1[CH:36]=[CH:35][C:34]([N:37]=[N:38][C:39](=[C:43]2[C:52]3[C:47](=[CH:48][CH:49]=[CH:50][CH:51]=3)[CH2:46][C:45]([CH3:54])([CH3:53])[NH:44]2)[C:40]([NH2:42])=[O:41])=[CH:33][CH:32]=1)(=[O:30])[CH3:29]>C(#N)C>[C:28]([C:31]1[CH:32]=[CH:33][C:34]([N:37]=[N:38][CH:39]([CH:43]2[C:52]3[C:47](=[CH:48][CH:49]=[CH:50][CH:51]=3)[CH2:46][C:45]([CH3:54])([CH3:53])[NH:44]2)[C:40]([NH2:42])=[O:41])=[CH:35][CH:36]=1)(=[O:30])[CH3:29]

参加物

5

反応物 3

HCID 6460TriphenylstannaneHCID 7237O-XyleneHCID 178466770HCID 178466770、化合物

生成物 1

HCID 11152734HCID 11152734、化合物

試薬・触媒・溶媒 1

HCID 6342Acetonitrile溶媒

実験手順

In a nitrogen atmosphere, 2-(4-acetyl-phenylazo)-2-(3,3-dimethyl-3,4-dihydro-2H-isoquinoline-1-ylidene)-acetamide (Asinex Corp., Russia) is dissolved in acetonitrile, and the obtained product is added with xylene in which triphenyl tin hydride (Aldrich, Corp., USA) is dissolved, and the mixture is refluxed. The refluxed product is cooled to room temperature and an insoluble matter is separated by filtration. The solvent is removed from the filtrate by reducing the pressure. The residue containing the reaction product is purified by column chromatography to obtain the title compound.

後処理

  1. dissolutionis dissolved
  2. temperaturethe mixture is refluxed
  3. customan insoluble matter is separated by filtration
  4. customThe solvent is removed from the filtrate
  5. additionThe residue containing the reaction product
  6. customis purified by column chromatography

出典と根拠

ORDレコード
ord-ce31b888ce6146548f9a61256b784f0d
出典データセット
uspto-grants-2014_11
特許番号
US08883504B2

関連ノート

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