Hydrochloric Acid → HCID 68273173、化合物

HRID 334840

反応式

HRID 334840 の反応式
[N:1]1[N:2]([C:10]2[CH:15]=[C:14]([C:16]([CH3:23])([CH3:22])[CH2:17][C:18]([CH3:21])([CH3:20])[CH3:19])[CH:13]=[CH:12][C:11]=2O)[N:3]=[C:4]2[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=12.[CH2:25]=[O:26].[ClH:27]>C(O)(=O)C.[Cl-].[Zn+2].[Cl-]>[N:1]1[N:2]([C:10]2[CH:15]=[C:14]([C:16]([CH3:23])([CH3:22])[CH2:17][C:18]([CH3:21])([CH3:20])[CH3:19])[CH:13]=[C:12]([CH2:11][Cl:27])[C:25]=2[OH:26])[N:3]=[C:4]2[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=12

参加物

6

反応物 3

HCID 313Hydrochloric AcidHCID 712FormaldehydeHCID 62485Octrizole

生成物 1

HCID 68273173HCID 68273173、化合物

試薬・触媒・溶媒 2

HCID 3007855Zincchloride触媒HCID 176Acetic Acid溶媒

実験手順

2-(2H-Benzotriazol-2-yl)-4-(1,1,3,3-tetramethyl-butyl)phenol (45.0 g, 140 mmol) is dissolved in acetic acid (200 mL) at 90° C. Zinc chloride (2.0 g, 14 mmol) and paraformaldehyde (18 g, 600 mmol) are added and HCl gas is passed through the reaction mixture for 12 hours at 90° C. The product, which precipitates after cooling to room temperature, is filtered off, washed with cold pentane and dried at 60° C. under vacuum to yield 36 g of 2-(2H-Benzotriazol-2-yl)-6-chloromethyl-4-(1,1,3,3-tetramethyl-butyl)-phenol.

後処理

  1. customThe product, which precipitates
  2. filtrationis filtered off
  3. washwashed with cold pentane
  4. customdried at 60° C. under vacuum

出典と根拠

ORDレコード
ord-5d8960d93a87475bb6d1bad0107b651b
出典データセット
uspto-grants-2014_11
特許番号
US08883829B2

関連ノート

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