関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Ethylenediamine | HCID 3301 | — |
| 反応物 | 4,4'-Difluorobenzil | HCID 123072 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | HCID 12342949 | HCID 12342949 | 93% |
反応手順
First, with dehydrated ethanol as a solvent, 16.8 g of 4,4′-difluorobenzil (by Tokyo Chemical Industry Co., Ltd.) and 4.5 g of ethylenediamine (by Kanto Chemical Co., Inc.) were mixed, and the mixture was refluxed at 105° C. for six hours. After reaction, a reaction solution was condensed by using an evaporator, and an obtained residue was recrystallized by using ethanol; thus, 2,3-bis(4-fluorophenyl)-5,6-dihydropyrazine was obtained (reddish brown powder, yield: 93%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08889266B2 |
|---|
| 出典データセット | uspto-grants-2014_11 |
|---|
| ORD ID | ord-5b95d9154a5644eea1e5aba8b5bc9550 |
|---|
| 出典メモ | uspto-grants-2014_11 |
|---|
