Sodium Azide → tert-Butyl 2-azido-6-azaspiro[3.4]octane-6-carboxylate
反応式
CS(O[CH:6]1[CH2:9][C:8]2([CH2:13][CH2:12][N:11]([C:14]([O:16][C:17]([CH3:20])([CH3:19])[CH3:18])=[O:15])[CH2:10]2)[CH2:7]1)(=O)=O.[N-:21]=[N+:22]=[N-:23].[Na+]>>[N:21]([CH:6]1[CH2:9][C:8]2([CH2:13][CH2:12][N:11]([C:14]([O:16][C:17]([CH3:20])([CH3:19])[CH3:18])=[O:15])[CH2:10]2)[CH2:7]1)=[N+:22]=[N-:23]参加物
3
実験手順
The process is performed according to the procedure described in Example 6 (step 6.3.). Starting with 1.62 g (5.30 mmol) of tert-butyl 2-methanesulfonyloxy-6-azaspiro[3.4]octane-6-carboxylate (isomer 1′), described in Example 12 (step 12.1.), and 0.68 g (10.61 mmol) of sodium azide, the product is obtained in the form of a yellow oil, which is used without further purification in the following step.
後処理
- customthe product is obtained in the form of a yellow oil, which
- customis used without further purification in the following step