Tetramethyl orthocarbonate → 5-(3-Bromophenyl)-2-methoxy-6,6-dimethyl-5,6-dihydro-1,4,3-oxathiazine 4,4-dioxide

HRID 339839

反応式

HRID 339839 の反応式
[Br:1][C:2]1[CH:3]=[C:4]([CH:8]([S:13]([NH2:16])(=[O:15])=[O:14])[C:9]([OH:12])([CH3:11])[CH3:10])[CH:5]=[CH:6][CH:7]=1.[CH3:17][O:18][C:19](OC)(OC)OC>C(O)(=O)C>[Br:1][C:2]1[CH:3]=[C:4]([CH:8]2[C:9]([CH3:10])([CH3:11])[O:12][C:17]([O:18][CH3:19])=[N:16][S:13]2(=[O:14])=[O:15])[CH:5]=[CH:6][CH:7]=1

参加物

4

反応物 2

HCID 74613Tetramethyl orthocarbonateHCID 682918601-(3-Bromophenyl)-2-hydroxy-2-methylpropane-1-sulfonamide

生成物 1

HCID 683592025-(3-Bromophenyl)-2-methoxy-6,6-dimethyl-5,6-dihydro-1,4,3-oxathiazine 4,4-dioxide

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒

反応条件

温度
100 °C

実験手順

A mixture of 500 mg of 1-(3-bromophenyl)-2-hydroxy-2-methylpropane-1-sulfonamide in 2 ml of tetramethoxymethane and 0.5 ml of acetic acid was stirred at 100° C. for 3 hours. After the removal of the solvent under reduced pressure, the residue (565 mg) was used in the next reaction without further purification.

後処理

  1. customAfter the removal of the solvent under reduced pressure
  2. customthe residue (565 mg) was used in the next reaction without further purification

出典と根拠

ORDレコード
ord-da8c1461b04e494cb05814fd65140e10
出典データセット
uspto-grants-2014_11
特許番号
US08895547B2

関連ノート

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