Hydrochloric Acid → 1-((Dimethylamino)methyl)cyclopropanecarboxylic acid
反応式
C([O:3][C:4]([C:6]1([CH2:9][N:10]([CH3:12])[CH3:11])[CH2:8][CH2:7]1)=[O:5])C.[OH-].[Na+].Cl>C(O)C>[CH3:11][N:10]([CH2:9][C:6]1([C:4]([OH:5])=[O:3])[CH2:8][CH2:7]1)[CH3:12]参加物
5
実験手順
To a solution of 222 mg of 1-dimethylaminomethyl-cyclopropane carboxylic acid ethyl ester in 0.4 mL of ethanol was added 0.1 mL of 5N sodium hydroxide aqueous solution, and stirred overnight at room temperature. The reaction solution was added with 0.5 mL of 1N hydrochloric acid, and the solvent and water were evaporated, to give 78 mg of a mixture of the title compound and sodium chloride as a white powder.
後処理
- customthe solvent and water were evaporated
出典と根拠
- ORDレコード
- ord-0c5b3d9ae7dd417b88006538662a5308
- 出典データセット
- uspto-grants-2008_09
- 特許番号
- US07429609B2
反応ノート
読み込み中…