Sodium Hydroxide → Sodium 3-methoxypyridine-2-carboxylate
反応式
[CH3:1][O:2][C:3]1[C:4]([C:9]([O:11]C)=[O:10])=[N:5][CH:6]=[CH:7][CH:8]=1.[OH-].[Na+:14]>CO>[CH3:1][O:2][C:3]1[C:4]([C:9]([O-:11])=[O:10])=[N:5][CH:6]=[CH:7][CH:8]=1.[Na+:14]参加物
4
実験手順
To a stirred solution of methyl 3-methoxypyridine-2-carboxylate (Intermediate 95, 0.55 g, 3.3 mmol) in methanol (10 ml) was added dropwise aqueous sodium hydroxide solution (1M, 4 ml, 4 mmol). The mixture was left to stand overnight. The mixture was concentrated under vacuum to give a white solid, which was used without further purification or characterisation.
後処理
- waitThe mixture was left
- concentrationThe mixture was concentrated under vacuum
- customto give a white solid, which
- customwas used without further purification or characterisation
出典と根拠
- ORDレコード
- ord-bb216226dc1f43a8afb8db2a6f90938b
- 出典データセット
- uspto-grants-2014_11
- 特許番号
- US08895733B2
反応ノート
読み込み中…