2,6-Dichloro-3-methylaniline → N-(2,6-Dichloro-3-methylphenyl)-4,6-dimethyl-2-pyrimidinesulfonamide

HRID 34252

反応式

HRID 34252 の反応式
[Cl:1][C:2]1[C:8]([CH3:9])=[CH:7][CH:6]=[C:5]([Cl:10])[C:3]=1[NH2:4].[CH3:11][C:12]1[CH:17]=[C:16]([CH3:18])[N:15]=[C:14]([S:19](F)(=[O:21])=[O:20])[N:13]=1>>[Cl:1][C:2]1[C:8]([CH3:9])=[CH:7][CH:6]=[C:5]([Cl:10])[C:3]=1[NH:4][S:19]([C:14]1[N:13]=[C:12]([CH3:11])[CH:17]=[C:16]([CH3:18])[N:15]=1)(=[O:20])=[O:21]

参加物

3

反応物 2

HCID 1165292,6-Dichloro-3-methylanilineHCID 144047184,6-Dimethylpyrimidine-2-sulfonyl fluoride

生成物 1

HCID 14404704N-(2,6-Dichloro-3-methylphenyl)-4,6-dimethyl-2-pyrimidinesulfonamide

実験手順

This material was prepared from 2,6-dichloro-3-methylaniline and 4,6-dimethyl-2-pyrimidinesulfonyl fluoride following the general procedure described in Example 2. The desired product was isolated as a solid, m.p. 234°-235°. NMR (90 MHZ) D6 -Acetone: δ 7.4 (d, 2H), 7.3 (s, 1H), 2.5 (s, 6H) and 2.3 (s, 3H).

出典と根拠

ORDレコード
ord-ecd2f98b80d3423c9e2f3a399d300e50
出典データセット
uspto-grants-1988_08
特許番号
US04761173

関連ノート

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