Benzaldehyde → Ethyl 2-benzylideneaminobutyrate

HRID 342865

反応式

HRID 342865 の反応式
C(N(CC)CC)C.Cl.[NH2:9][CH:10]([CH2:16][CH3:17])[C:11]([O:13][CH2:14][CH3:15])=[O:12].[CH:18](=O)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>C1(C)C=CC=CC=1>[CH:18](=[N:9][CH:10]([CH2:16][CH3:17])[C:11]([O:13][CH2:14][CH3:15])=[O:12])[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

参加物

5

反応物 3

HCID 240BenzaldehydeHCID 8471TriethylamineHCID 12844023Ethyl 2-Aminobutyrate Hydrochloride

生成物 1

HCID 10331026Ethyl 2-benzylideneaminobutyrate

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

Triethylamine (2 moles) was added to a solution of the product from step (a) (1 mole) in toluene. When addition was complete, benzaldehyde (1 mole) was added. The mixture was azeotroped until no further water was collected, then cooled to room temperature and filtered. The filtrate was evaporated in vacuo ti give the desired product as an oil.

後処理

  1. additionWhen addition
  2. customThe mixture was azeotroped until no further water
  3. customwas collected
  4. filtrationfiltered
  5. customThe filtrate was evaporated in vacuo ti

出典と根拠

ORDレコード
ord-410984a921a147c6bb9ce5296f537673
出典データセット
uspto-grants-1999_01
特許番号
US05859240

関連ノート

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