Trimethylsilyl cyanide → 4-Bromo-2-cyanopyridine

HRID 343319

反応式

HRID 343319 の反応式
[Br:1][C:2]1[CH:7]=[CH:6][N+:5]([O-])=[CH:4][CH:3]=1.C[Si]([C:13]#[N:14])(C)C>>[Br:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]([C:13]#[N:14])[CH:3]=1

参加物

3

反応物 2

HCID 82115Trimethylsilyl cyanideHCID 1397084-Bromopyridin-1-ium-1-olate

生成物 1

HCID 6932834-Bromo-2-cyanopyridine

実験手順

The title compound was prepared from 4-bromo-pyridine-1-oxide (Rec. Trav. chime, 1951, 70, 581) and trimethylsilyl cyanide, using the procedure described in Chem. Pharm. Bull., 1985, 33, 565, and obtained as a solid (49% yield), m.p. 88°-93° C. Rf 0.53 (SS 11). Found: C,39.15; H,1.50; N,15.07. C6H3BrN2 requires C,39.37; H,1.65; N,15.30%.

出典と根拠

ORDレコード
ord-2b6e3232d8d6463cb659dfe0d57906c0
出典データセット
uspto-grants-1999_01
特許番号
US05861393

関連ノート

読み込み中…