Sodium Hydroxide → Dehydroabietylamine

HRID 343475ノート

反応式

HRID 343475 の反応式
[CH3:1][CH:2]([C:4]1[CH:9]=[CH:8][C:7]2[C@:10]3([CH3:21])[C@@H:15]([CH2:16][CH2:17][C:6]=2[CH:5]=1)[C@@:14]([CH2:19][NH2:20])([CH3:18])[CH2:13][CH2:12][CH2:11]3)[CH3:3].CC(O)=O.[OH-].[Na+]>O>[CH3:3][CH:2]([C:4]1[CH:9]=[CH:8][C:7]2[C@:10]3([CH3:21])[C@@H:15]([CH2:16][CH2:17][C:6]=2[CH:5]=1)[C@@:14]([CH2:19][NH2:20])([CH3:18])[CH2:13][CH2:12][CH2:11]3)[CH3:1]

参加物

4

反応物 2

HCID 14798Sodium HydroxideHCID 62418Dehydroabietylamine acetate

生成物 1

HCID 62034Dehydroabietylamine収率 76.6%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

A solution of dehydroabietylamine acetate (47 g, 0.16 mol) in water (175 mL) was gently warmed until the solution became homogeneous. An aqueous solution of NaOH (10% W/V, 61 mL) was carefully added and after cooling to room temperature. The aqueous solution was extracted with diethyl ether, dried over MgSO4, filtered and concentrated to give dehydroabietylamine (35 g, 58%) as a viscous oil which solidified on standing.

後処理

  1. extractionThe aqueous solution was extracted with diethyl ether
  2. dry with materialdried over MgSO4
  3. filtrationfiltered
  4. concentrationconcentrated

出典と根拠

ORDレコード
ord-c97f943c6d5c4f548026050a2ac90856
出典データセット
uspto-grants-1999_01
特許番号
US05861427

反応ノート

読み込み中…