Ethyl Acetate → 1-(2,3-Dihydro-1,4-benzodioxin-5-yl)butan-1,3-dione

HRID 343849

反応式

HRID 343849 の反応式
[O:1]1[C:6]2[CH:7]=[CH:8][CH:9]=[C:10]([C:11](=[O:13])[CH3:12])[C:5]=2[O:4][CH2:3][CH2:2]1.[H-].[Na+].[C:16](OCC)(=[O:18])[CH3:17]>>[O:1]1[C:6]2[CH:7]=[CH:8][CH:9]=[C:10]([C:11](=[O:13])[CH2:12][C:16](=[O:18])[CH3:17])[C:5]=2[O:4][CH2:3][CH2:2]1

参加物

4

反応物 3

HCID 8857Ethyl AcetateHCID 24758Sodium hydrideHCID 212680521-(2,3-Dihydro-1,4-benzodioxin-5-yl)ethanone

生成物 1

HCID 218462911-(2,3-Dihydro-1,4-benzodioxin-5-yl)butan-1,3-dione

反応条件

温度
80 °C

実験手順

1-(2,3-Dihydro-1,4-benzodioxin-5-yl)-ethanone (1.2 g) was dissolved in 20 mL of ethyl acetate, and sodium hydride (0.33 g, 60% oil dispersion) was added. The reaction mixture was heated to 80° C. overnight, quenched with water, and neutralized with carbon dioxide to give an oily product of 1-(2,3-dihydro-1,4-benzodioxin-5-yl)butan-1,3-dione (0.37 g).

後処理

  1. customquenched with water

出典と根拠

ORDレコード
ord-06f774e4cdc34a89887580b0be431f69
出典データセット
uspto-grants-1999_01
特許番号
US05863924

関連ノート

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