化工社化工社 化学情報印刷レポート · 研究参考用
4-Nitrobenzaldehyde → 4-Amino-5-chloro-2-methoxy-N-((1-(5-(4-nitrobenzylamino)pentyl)-piperidin-4-yl)methyl)benzamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Nitrobenzaldehyde | HCID 541 | — |
| 反応物 | 4-Amino-N-(1-(5-aminopentyl)piperidin-4-ylmethyl)-5-chloro-2-methoxybenzamide | HCID 54008363 | — |
| 生成物 | 4-Amino-5-chloro-2-methoxy-N-((1-(5-(4-nitrobenzylamino)pentyl)-piperidin-4-yl)methyl)benzamide | HCID 54448865 | 85% |
反応手順
4-Amino-N-(1-(5-aminopentyl)piperidin-4-ylmethyl)-5-chloro-2-methoxybenzamide (2 g) as starting compound and 4-nitrobenzaldehyde (0.87 g) were reacted and treated in the same manner as in Example 121 to give 2.3 g of 4-amino-5-chloro-2-methoxy-N-((1-(5-(4-nitrobenzylamino)pentyl)piperidin-4-yl)methyl)benzamide.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05864039 |
| 出典データセット | uspto-grants-1999_01 |
| ORD ID | ord-f8ca7c0c939448e2b83cf3607407c35e |
| 出典メモ | uspto-grants-1999_01 |