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HRID344397

反应详情

EQUATION

反应方程式

HRID 344397 的结构方程式

REACTANTS

反应物

2
结构：O=Cc1ccc([N+](=O)[O-])cc1
HCID541

4-Nitrobenzaldehyde

C7H5NO3

结构：COc1cc(N)c(Cl)cc1C(=O)NCC1CCN(CCCCCN)CC1
HCID54008363

未命名化合物

PRODUCTS

生成物

1
结构：COc1cc(N)c(Cl)cc1C(=O)NCC1CCN(CCCCCNCc2ccc([N+](=O)[O-])cc2)CC1
HCID54448865

未命名化合物

收率 85%

PROCEDURE

实验过程

4-Amino-N-(1-(5-aminopentyl)piperidin-4-ylmethyl)-5-chloro-2-methoxybenzamide (2 g) as starting compound and 4-nitrobenzaldehyde (0.87 g) were reacted and treated in the same manner as in Example 121 to give 2.3 g of 4-amino-5-chloro-2-methoxy-N-((1-(5-(4-nitrobenzylamino)pentyl)piperidin-4-yl)methyl)benzamide.

WORKUP

后处理

  1. customwere reacted
  2. additiontreated in the same manner as in Example 121