化工社化工社 化学情報印刷レポート · 研究参考用
Ethylene Glycol → 2-[(beta-Hydroxyethoxy)methyl]-4-nitrophenol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethylene Glycol | HCID 174 | — |
| 反応物 | 2-(Chloromethyl)-4-nitrophenol | HCID 76305 | — |
| 生成物 | 2-[(beta-Hydroxyethoxy)methyl]-4-nitrophenol | HCID 19770509 | — |
反応手順
6.5 moles (93.8 g) of 2-hydroxy-5-nitrobenzyl chloride are heated for 4 hours in 150 ml of ethylene glycol on a boiling water bath. The expected product crystallizes after dilution of the reaction mixture with a litre of iced water. After filtering off followed by drying at 40° C. under air vacuum the product obtained is recrystallized from isopropyl acetate. It melts at 132° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05053052 |
| 出典データセット | uspto-grants-1991_10 |
| ORD ID | ord-adfbf402b4a5489faab2c47bad63b721 |
| 出典メモ | uspto-grants-1991_10 |