Tetrahydrophthalic anhydride → HCID 12881900、化合物

HRID 344592

反応式

HRID 344592 の反応式
[CH2:1]1[CH:6]2[C:7]([O:9][C:10](=[O:11])[CH:5]2[CH2:4][CH:3]=[CH:2]1)=O.[CH2:12]([O:15][C:16]1[CH:17]=[C:18]([CH:20]=[CH:21][C:22]=1[Cl:23])[NH2:19])[CH:13]=[CH2:14]>C(O)(=O)C>[CH2:12]([O:15][C:16]1[CH:17]=[C:18]([N:19]2[C:10](=[O:11])[C:5]3[CH2:4][CH2:3][CH2:2][CH2:1][C:6]=3[C:7]2=[O:9])[CH:20]=[CH:21][C:22]=1[Cl:23])[CH:13]=[CH2:14]

参加物

4

反応物 2

HCID 6810Tetrahydrophthalic anhydrideHCID 544961134-Chloro-3-[(prop-2-en-1-yl)oxy]aniline

生成物 1

HCID 12881900HCID 12881900、化合物

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒

実験手順

A mixture of 4.4 g of THPA, 5.3 g of 3B and 60 mL of glacial acetic acid was refluxed for 1 hour, then poured into 300 mL of ice water. The resulting mixture was allowed to stand for 10 minutes, then filtered. The collected solid was washed with cold water, dried under reduced pressure and recrystallized from ethyl acetate/hexane, to give N-(3-(allyloxy)-4-chlorophenyl)-3,4,5,6-tetrahydrophthalimide (3C), as yellow crystals, m.p.: 118.5°-120° C.

後処理

  1. temperaturewas refluxed for 1 hour
  2. filtrationfiltered
  3. washThe collected solid was washed with cold water
  4. customdried under reduced pressure
  5. customrecrystallized from ethyl acetate/hexane

出典と根拠

ORDレコード
ord-93160ebf2a4a4814a78be9c823f58fad
出典データセット
uspto-grants-1991_10
特許番号
US05053071

関連ノート

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