4-Acetamidopyridine acetate → HCID 70155070、化合物
反応式
[C:1]([OH:4])(=[O:3])[CH3:2].[C:5]([NH:8][C:9]1[CH:14]=[CH:13][N:12]=[CH:11][CH:10]=1)(=[O:7])[CH3:6].[H][H]>C(O)(=O)C.O=[Pt]=O>[C:1]([OH:4])(=[O:3])[CH3:2].[C:5]([NH:8][CH:9]1[CH2:14][CH2:13][NH:12][CH2:11][CH2:10]1)(=[O:7])[CH3:6]参加物
5
実験手順
A solution of the product of Example 2 (75 g) in 750 mL acetic acid was reduced over PtO2 catalyst at 60 psi hydrogen atmosphere at 60° C. for 7 hours. The solution was filtered, concentrated and triturated with ether to afford the title compound quantitatively as a white solid which was used directly in subsequent reactions.
後処理
- filtrationThe solution was filtered
- concentrationconcentrated
- customtriturated with ether
出典と根拠
- ORDレコード
- ord-76012d890f2b4e97bf59c6f39a205ece
- 出典データセット
- uspto-grants-1991_10
- 特許番号
- US05053413
反応ノート
読み込み中…