Methyl iodide → 1-Methyl-3-(oxazol-2-yl)-pyridinium iodide

HRID 344691ノート

反応式

HRID 344691 の反応式
[O:1]1[CH:5]=[CH:4][N:3]=[C:2]1[C:6]1[CH:7]=[N:8][CH:9]=[CH:10][CH:11]=1.[CH3:12][I:13]>C(O)C>[I-:13].[CH3:12][N+:8]1[CH:9]=[CH:10][CH:11]=[C:6]([C:2]2[O:1][CH:5]=[CH:4][N:3]=2)[CH:7]=1

参加物

4

反応物 2

HCID 6328Methyl iodideHCID 204053873-(1,3-Oxazol-2-yl)pyridine

生成物 1

HCID 679250871-Methyl-3-(oxazol-2-yl)-pyridinium iodide

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

11.3 g of [(3-oxazol-2-yl)-pyridine] prepared as indicated in Helv. Chim. Acta 45 375 (1962) and 22.4 g of methyl iodide in 150 cm3 of ethanol are heated under reflux for 2 hours, then the reaction medium is left for 2 days. The solvent is evaporated, the residue is crystallized from 95° ethanol and 17 g of product is obtained. M.p.=241° C. (decomp.) after recrystallization from ethanol.

後処理

  1. temperatureunder reflux for 2 hours
  2. customThe solvent is evaporated
  3. customthe residue is crystallized from 95° ethanol

出典と根拠

ORDレコード
ord-930f310ea1c64ef5ae73e7b18080b2e8
出典データセット
uspto-grants-1991_10
特許番号
US05053416

反応ノート

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