Ethanolamine → 138148-37-5

反応式

[CH2:1]([CH2:3][NH2:4])[OH:2].C[O:6][C:7](=O)[CH2:8][CH2:9][NH:10][C:11](=[O:13])[CH3:12]>>[C:11]([NH:10][CH2:9][CH2:8][C:7]([NH:4][CH2:3][CH2:1][OH:2])=[O:6])(=[O:13])[CH3:12]

参加物

反応物 2

HCID 700Ethanolamine

HCID 12859671Methyl N-acetyl-beta-alaninate

生成物 1

HCID 19805630138148-37-5収率 62.6%

反応条件

温度: 85 °C

実験手順

A mixture of 0.42 g of ethanolamine and 1.0 g of N-acetyl-β-alanine methyl ester was heated at 85° C. for 4 hours. The resulting yellow oil solidified upon cooling and was crystallized from acetonitrile, giving 0.75 g of the desired compound as a white solid, mp 122-125° C.

後処理

temperatureupon cooling
customwas crystallized from acetonitrile

出典と根拠

ORDレコード: ord-d65c514e95c846b281f498b931691aab
出典データセット: uspto-grants-1991_10
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05053426

反応ノート

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