関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | 3-Chloropropionyl chloride | HCID 69364 | — |
| 反応物 | 2(1H)-Pyrimidinone, tetrahydro- | HCID 74615 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | (3-Chloropropanoyl)urea | HCID 12937417 | 79.8% |
反応手順
20.0 g of N,N'-trimethyleneurea are partially dissolved in 1000 ml of toluene under reflux and admixed with 20.2 g of triethylamine and then dropwise, in the course of 90 minutes, with a solution of 25.4 g of 3-chloropropionyl chloride. Subsequent stirring for 30 minutes, cooling down to 5° C., removal of undissolved matter by filtration and evaporating the filtrate in vacuo gives 24 g of chloropropionylurea of the formula ##STR70## as a beige powder.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05055567 |
|---|
| 出典データセット | uspto-grants-1991_10 |
|---|
| ORD ID | ord-e25446250eeb40bdb22986ef2666127e |
|---|
| 出典メモ | uspto-grants-1991_10 |
|---|
