反应详情

温度

5 °C

20.0 g of N,N'-trimethyleneurea are partially dissolved in 1000 ml of toluene under reflux and admixed with 20.2 g of triethylamine and then dropwise, in the course of 90 minutes, with a solution of 25.4 g of 3-chloropropionyl chloride. Subsequent stirring for 30 minutes, cooling down to 5° C., removal of undissolved matter by filtration and evaporating the filtrate in vacuo gives 24 g of chloropropionylurea of the formula ##STR70## as a beige powder.

1. temperatureunder reflux
2. customin the course of 90 minutes
3. customremoval of undissolved matter
4. filtrationby filtration
5. customevaporating the filtrate in vacuo