Allyl chloride → N-Allyl-N-(1,1-dimethoxyprop-2-yl)-urethane

HRID 345817

反応式

HRID 345817 の反応式
[CH3:1][O:2][CH:3]([O:12][CH3:13])[CH:4]([NH:6][C:7]([O:9][CH2:10][CH3:11])=[O:8])[CH3:5].[H-].[Na+].[H][H].[CH2:18](Cl)[CH:19]=[CH2:20]>C1(C)C=CC=CC=1>[CH2:20]([N:6]([CH:4]([CH3:5])[CH:3]([O:2][CH3:1])[O:12][CH3:13])[C:7]([O:9][CH2:10][CH3:11])=[O:8])[CH:19]=[CH2:18]

参加物

6

反応物 4

HCID 7850Allyl chlorideHCID 24758Sodium hydrideHCID 15069987N-(1,1-dimethoxyprop-2-yl)urethaneHCID 178418361HCID 178418361、化合物

生成物 1

HCID 15069988N-Allyl-N-(1,1-dimethoxyprop-2-yl)-urethane

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

反応条件

温度
90 °C

実験手順

131 g (0.686 mol) of N-(1,1-dimethoxyprop-2-yl)urethane are added dropwise to 25 g of sodium hydride (80% strength) in 700 ml of absolute toluene at 90° C. When the evolution of hydrogen has ended, 61.2 g (0.8 mol) of allyl chloride are added dropwise at 90° C. and the mixture is stirred overnight at 90° C. The sodium chloride which has precipitated out is dissolved with water, the organic phase is separated off, dried over K2CO3 and concentrated and the residue is distilled.

後処理

  1. customThe sodium chloride which has precipitated out
  2. dissolutionis dissolved with water
  3. customthe organic phase is separated off
  4. dry with materialdried over K2CO3
  5. concentrationconcentrated
  6. distillationthe residue is distilled

出典と根拠

ORDレコード
ord-83598b0e23e2489da6c4b17e1611b235
出典データセット
uspto-grants-1991_10
特許番号
US05059597

関連ノート

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