Acetic Acid → HCID 14405001、化合物
反応式
[Cl:1][C:2]1[C:7]([F:8])=[CH:6][C:5]([F:9])=[C:4]([Cl:10])[C:3]=1[OH:11].C(O)(=O)C.[N+:16]([O-])([OH:18])=[O:17]>ClCCl>[Cl:1][C:2]1[C:7]([F:8])=[C:6]([N+:16]([O-:18])=[O:17])[C:5]([F:9])=[C:4]([Cl:10])[C:3]=1[OH:11]参加物
5
実験手順
20 g of 2,6-dichloro-3,5-difluorophenol are initially introduced into 70 ml of acetic acid, and 8 g of 98% strength nitric acid are added dropwise. Subsequently, the mixture is then stirred for 2 hours at room temperature, taken up in 150 ml of dichloromethane and washed twice with water. 18 g of product remain after distilling off the dichloromethane. 94% pure in accordance with GC analysis.
後処理
- additionare added dropwise
- washwashed twice with water
- distillationafter distilling off the dichloromethane
出典と根拠
- ORDレコード
- ord-38eeb9562c7345a98cc33b754b192c11
- 出典データセット
- uspto-grants-1991_10
- 特許番号
- US05059623
反応ノート
読み込み中…